�AstraZeneca announced new SEROQUEL XR� (protracted release quetiapine fumarate) clinical study information in patients with Generalised Anxiety Disorder (GAD), presented at the 21st European College of Neuropsychopharmacology (ECNP) Congress in Barcelona. In this study, extended handout quetiapine fumarate significantly improved symptoms of anxiety at Week 8 compared with placebo and this was observed as early as day 4. The active comparator branch, escitalopram 10mg/day, was as well effective at improving symptoms of GAD at week 8 compared with placebo although improvement was not observed at day 4.
During their lifetimes, it is estimated between 2.7% and 5.4% of people in Europe will suffer from GAD.1 Characteristic symptoms include chronic anxiety, enlarged worry and tension - it is often attended by depression or other anxiety disorders2,3 - and it has a substantial negative impact on Health-Related Quality of Life (HRQoL), productiveness at shape (including absenteeism) and healthcare costs1.
Antidepressants (SSRIs (selective-serotonin reuptake inhibitors) and SNRIs (serotonin and norepinephrine reuptake inhibitors)) are standard treatments that ar generally efficacious but or so 30 per centum of patients treated with SSRIs or SNRIs testament have an inadequate response4. Additionally, they may have got a comparatively slow attack of action, sometimes requiring combination with a myopic course of benzodiazepines (BZDs) to accomplish initial symptom control - however, BZDs may have the potential for dependence and detachment symptoms5.
The data presented today in Barcelona ar the results of Study 10 - conducted across 64 centres in the U.S. and part of the clinical development program for extended release quetiapine fumarate for the treatment of GAD6. A add together of 854 patients aged 18-65 with a DSM-IV3 diagnosis of GAD were randomized to receive either extended vent quetiapine fumarate 150mg/day (n=219), 300mg/day (n=207), escitalopram 10mg/day (n=213) or placebo (n=215). At workweek 8, prolonged release quetiapine fumarate 150mg/day, 300mg/day and escitalopram 10mg/day, significantly decreased mean Hamilton Anxiety Rating Scale (HAM-A) total stacks from randomization compared with placebo (13.9 [p
Both extended tone ending quetiapine fumarate and escitalopram were generally well tolerated. Among lengthened release quetiapine fumarate treated patients, untoward events with incidence greater than 10% and double that of placebo were dry mouth, somnolence, drugging and constipation; among escitalopram-treated patients they were sedation and sickness.
The incidence of AEs associated with EPS among patients treated with extended release quetiapine fumarate 150mg/day, 300mg/day, escitalopram 10mg/day or placebo were 4.2%, 6.0%, 6.8% and 5.7% respectively; the incidence of AEs associated with sexual dysfunction were were 4.1%, 3.9%, 8.1% and 3.7% severally. The proportions of patients who experienced a clinically important budge in fast blood glucose (from normal to >126mg/dL) were 3.7%, 1.6%, 1.1% and 3.2% in the quetiapine fumarate 150mg/day, 300mg/day, escitalopram 10mg/day or placebo groups, severally; the proportions of patients experiencing >7% increase in weight were 3.8%, 3.9%, 0.5% and 0.9% respectively6.
About Generalized Anxiety Disorder (GAD)
GAD is characterized by chronic anxiety, magnified worry, and tension, even when thither is little or zippo to harass it. People with GAD anticipate disaster and are overly interested about health issues, money, family problems, or difficulties at work.2,3
People with GAD can't seem to get rid of their concerns, even though they usually realize that their anxiety is more intense than the place warrants. They can't relax, startle well, and have got difficulty concentrating. Often they have hassle falling asleep or staying asleep. Physical symptoms that often accompany the anxiety include fatigue, headaches, musculus tension, muscle aches, difficulty swallowing, quivering, twitching, excitability, sweating, nausea, lightheadedness, having to go to the bathroom oft, feeling out of breath, and hot flushes. GAD is diagnosed when somebody excessively worries about a number of everyday problems for at least 6 months2,3.
About SEROQUEL and SEROQUEL XR
In May 2008, SEROQUEL XR� (extended release quetiapine fumarate) became the first ever so antipsychotic to complete a clinical development programme and be filed with the FDA in the U.S. for commendation in the treatment of GAD7 - today it is not approved in any country for the treatment of GAD but remains under review with the FDA. SEROQUEL XR� is sanctioned in the US and 28 further countries for the treatment of schizophrenic disorder in grownup patients and for maintenance treatment of schizophrenia in adult patients. It was launched in the US in 2007 and earlier this year AstraZeneca announced the submission of regulatory applications in both the US and European Union for SEROQUEL XR in the treatment of frenzied episodes associated with bipolar disorder, and the handling of depressive episodes associated with bipolar disorder. An sNDA for SEROQUEL XR seeking commendation for the treatment of Major Depressive Disorder in the US was as well announced in February. SEROQUEL XR is not approved for these indications at this clock time and the applications remain under review by the regulatory authorities.
Launched in 1997, it is estimated that SEROQUEL has been prescribed to more than 22 million patients worldwide*. It is approved in 88 countries for the treatment of schizophrenia, in 79 countries for the treatment of bipolar manic disorder, and in 11 countries including the US for the discourse of bipolar depression. It was too recently sanctioned by the FDA in the USA for the for the maintenance treatment of patients with bipolar I upset, as adjunct to atomic number 3 or valproate - a similar submission has been made in Europe.
* Based on assumptions: (1) estimated turn of prescriptions per patient based upon IMS APLD data; and (2) IMS Prescription data for SEROQUEL covering 13 major markets in which this information is uncommitted since the time of launch.
About AstraZeneca
AstraZeneca is a major international healthcare stage business engaged in research, development, manufacturing and marketing of prescription pharmaceuticals and provider for health care services. AstraZeneca is one of the world's ahead pharmaceutical companies with health care sales of US $29.55 1000000000000 and is a leader in gI, cardiovascular, neuroscience, respiratory, oncology and infection product gross sales. AstraZeneca is listed in the Dow Jones Sustainability Index (Global) as substantially as the FTSE4Good Index.
http://www.astrazeneca.com
References
1 Wyrwich KW et al. A review of the humanistic and economic outcomes in European patients diagnosed with generalized anxiety disorder. Presented at the 161st Annual Meeting of the American Psychiatric Association, 2008. NR3-065.
2 National Institute of Mental Health: Anxiety Disorders. NIH Publication No. 06-3879. Available here. Accessed 5 August, 2008.
3 Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Association; 2000:472-475.
4 Bezerra de Menezes G, Fontenelle LF, Mulolo S et al. Treatment-resistant anxiety disorders: social phobic neurosis, generalized anxiety disorder and panic disorderliness. The Brazilian Journal of Psychiatry. 2007; 29(Supplement II):S55-60.
5 Nutt D, Argyropoulos S, Hood S et al. Generalized anxiety disorder: a comorbid disease. European Neuropsychopharmacology (2006) 16, S109-S118
6 Merideth C, Cutler LC196% Neijber A et al. Efficacy and tolerability of extended release quetiapine fumarate (Quetiapine XR) monotherapy in the treatment of GAD. twenty-first ECNP Congress, 2008.
7 Press release: AstraZeneca Submits sNDA for Seroquel XR� for the Treatment of Generalised Anxiety Disorder - a First for the Atypical Antipsychotic Class of Medicines. 8 May 2008. See: hypertext transfer protocol://www.astrazeneca.com/pressrelease/5392.aspx. Accessed 5 August, 2008.
http://www.astrazeneca.com
View drug information on Seroquel.
More info
Tuesday, 2 September 2008
Saturday, 23 August 2008
Mp3 music: Andy Narell
 Artist: Andy Narell: mp3 download Genre(s): Jazz New Age Andy Narell's discography:  The Passage Year: 2004 Tracks: 7  Live in South Africa Year: 2001 Tracks: 12  The Long Time Band Year: 1995 Tracks: 9 Andy Narell introduced the steel drums to jazz as a solo tool, playing not only Caribbean and Latin melodies only R&B, funk, and some straight-ahead jazz. After graduating from the University of California, Berkeley, in 1973, he founded the Hip Pocket mark (which became associated with Windham Hill) and has recorded on a regular base both as a leader and as a sideman ever since. In 1995, Andy Narell became a co-leader of the Caribbean Jazz Project along with Paquito d'Rivera and Dave Samuals, a perfect mercantile ecesis for his virtuosic and colored playing. Since that time, Narell has released a handful of recordings including, among others, Live in South Africa in 2001, Passage in 2004, and Tatoom in 2007. |
�90210� Trailer: Brenda! Kelly! Some Other People!
Wednesday, 13 August 2008
Study Shows Epidural Anaesthesia Is Safe But Only Slightly Improves Survival
�A sketch of quarter of a million patients has shows that epidural anaesthesia anaesthesia / analgesia* (EA) is safe for patients undergoing average to speculative surgery other than cardiac surgery. However people given EA possess only a very slightly increased selection compared with those world Health Organization do not. These ar the conclusions of authors of an Article promulgated early Online and in an forthcoming edition of The Lancet.
EA offers better postoperative pain in the neck relief than intravenous opioid drugs, and also reduces the surgical stress response, which has theoretical benefits for cardiovascular, respiratory, gastrointestinal, and metabolic function. But until now one authoritative question has remained unanswered: do these benefits of EA translate into improved survival for the patients who receive it? Dr Duminda Wijeysundera, from Ontario's Institute for Clinical Evaluative Sciences, and Department of Anaesthesia, Toronto General Hospital and University of Toronto, Canada, and colleagues did a retrospective study of 259 037 Ontario patients to enquire.
The patients in the study were all of age 40 years or over, and had had selected elective intermediate to risky non-cardiac surgery between 1994 and 2004. A total of 56 556 (22%) of these patients standard EA, and the procedure was associated with a small step-down in 30-day mortality (1�7%) compared with patients wHO had non had EA (2�0%). Put another way, 477 patients had to have had EA to avert one death.
The authors conclude: "Epidural anaesthesia was associated with a small improvement in 30-day survival, just this core should be interpreted conservatively. The estimate had borderline significance, despite a large sample size of it. Its absolute magnitude was also modest, corresponding to a number needed to treat of 477. Our study, consequently, does not provide compelling evidence that epidural anaesthesia improves postoperative survival. Nonetheless, our results support the safety of perioperative epidural anesthesia anaesthesia when used for indications other than improving survival - for lesson, improving postoperative pain relief or preventing postoperative lung complications."
In an incidental Comment, Dr Michael Barrington and Dr David Scott, Department of Anaesthesia, St Vincent's Hospital, Melbourne, VIC, Australia, say: "Wijeysundera and colleagues point out that our focus should be on the proven benefits of epidural anesthesia analgesia. The most durable and understandably defined benefit of epidural anaesthesia analgesia is improved analgesia. Provision of effective analgesia is our core job: it has substantial physiological and psychological benefits, and is regarded as a fundamental human right. Pain after major surgery canful be spartan, and we think that in many cases pain relief unequaled is an unambiguous clinical indication for postoperative epidural anesthesia analgesia."
"Epidural anaesthesia and survival after intermediate-to-high risk of exposure non-cardiac surgery: a population-based cohort study"
Duminda N Wijeysundera, W Scott Beattie, Peter C Austin, Janet E Hux, Andreas Laupacis
The Lancet - Published OnlineAugust 11, 2008DOI:10.1016/S0140-6736(08)61121-6
COMMENT
"Do we need to justify epidural analgesia beyond pain relief?"
The Lancet - Published OnlineAugust 11, 2008DOI:10.1016/S0140-6736(08)61122-8
http://www.thelancet.com
More info
EA offers better postoperative pain in the neck relief than intravenous opioid drugs, and also reduces the surgical stress response, which has theoretical benefits for cardiovascular, respiratory, gastrointestinal, and metabolic function. But until now one authoritative question has remained unanswered: do these benefits of EA translate into improved survival for the patients who receive it? Dr Duminda Wijeysundera, from Ontario's Institute for Clinical Evaluative Sciences, and Department of Anaesthesia, Toronto General Hospital and University of Toronto, Canada, and colleagues did a retrospective study of 259 037 Ontario patients to enquire.
The patients in the study were all of age 40 years or over, and had had selected elective intermediate to risky non-cardiac surgery between 1994 and 2004. A total of 56 556 (22%) of these patients standard EA, and the procedure was associated with a small step-down in 30-day mortality (1�7%) compared with patients wHO had non had EA (2�0%). Put another way, 477 patients had to have had EA to avert one death.
The authors conclude: "Epidural anaesthesia was associated with a small improvement in 30-day survival, just this core should be interpreted conservatively. The estimate had borderline significance, despite a large sample size of it. Its absolute magnitude was also modest, corresponding to a number needed to treat of 477. Our study, consequently, does not provide compelling evidence that epidural anaesthesia improves postoperative survival. Nonetheless, our results support the safety of perioperative epidural anesthesia anaesthesia when used for indications other than improving survival - for lesson, improving postoperative pain relief or preventing postoperative lung complications."
In an incidental Comment, Dr Michael Barrington and Dr David Scott, Department of Anaesthesia, St Vincent's Hospital, Melbourne, VIC, Australia, say: "Wijeysundera and colleagues point out that our focus should be on the proven benefits of epidural anesthesia analgesia. The most durable and understandably defined benefit of epidural anaesthesia analgesia is improved analgesia. Provision of effective analgesia is our core job: it has substantial physiological and psychological benefits, and is regarded as a fundamental human right. Pain after major surgery canful be spartan, and we think that in many cases pain relief unequaled is an unambiguous clinical indication for postoperative epidural anesthesia analgesia."
"Epidural anaesthesia and survival after intermediate-to-high risk of exposure non-cardiac surgery: a population-based cohort study"
Duminda N Wijeysundera, W Scott Beattie, Peter C Austin, Janet E Hux, Andreas Laupacis
The Lancet - Published OnlineAugust 11, 2008DOI:10.1016/S0140-6736(08)61121-6
COMMENT
"Do we need to justify epidural analgesia beyond pain relief?"
The Lancet - Published OnlineAugust 11, 2008DOI:10.1016/S0140-6736(08)61122-8
http://www.thelancet.com
More info
Wednesday, 6 August 2008
Beatles Recording Worth Its Weight in Pounds
More than 30 years later, the Beatles' records are smooth golden.
A latterly unearthed reel-to-reel tape of what is believed to be a Fab Four recording session from 1964 was auctioned online Tuesday for 9,300 pounds, or, $23,446 (including tax and handling fees), according to Cameo Auctioneers in the Berkshire
Thursday, 26 June 2008
Stud
Artist: Stud
Genre(s):
Industrial
Breakbeat
Discography:
Greetings, Fatherland
Year: 2007
Tracks: 10
I Saw The Future
Year: 2006
Tracks: 8
Thursday, 19 June 2008
Kiyoshi Yoshida
Artist: Kiyoshi Yoshida
Genre(s):
New Age
Discography:
Long Way To Japan
Year: 2001
Tracks: 13
Alec Empire
Wednesday, 11 June 2008
Sentenced
Artist: Sentenced
Genre(s):
Metal: Gothic
Metal
Rock
Metal: Death,Black
Discography:
The Funeral Album
Year: 2005
Tracks: 13
Ever-Frost
Year: 2005
Tracks: 2
The Cold White Light
Year: 2002
Tracks: 11
No One There
Year: 2002
Tracks: 2
Cold White Light
Year: 2002
Tracks: 11
Live In Paris (La Loco)
Year: 2000
Tracks: 11
Crimson
Year: 2000
Tracks: 11
Killing Me Killing You
Year: 1999
Tracks: 2
Frozen
Year: 1998
Tracks: 12
Story - A Recollection (Story - Greatest Kills) (Best Of, Compilation)
Year: 1997
Tracks: 13
Greatest Kills
Year: 1997
Tracks: 15
Down
Year: 1996
Tracks: 11
Love and Death
Year: 1995
Tracks: 5
Amok
Year: 1995
Tracks: 9
The Trooper
Year: 1993
Tracks: 4
North From Here
Year: 1993
Tracks: 8
Shadows Of The Past
Year: 1991
Tracks: 12
Live Tracks
Year:
Tracks: 2
The Finnish heavy metal dance band Sentenced released its debut record album, Shadows of the Past, in the early '90s on a little French judge; dissatisfied with their moderately commonplace black-metal good, they hired bassist/vocalist Taneli Jarva to allow more than originality for 1992's Second Earl of Guilford From Here. The criminal record was more than melodic and technically competent and got the band noticed in Sweden; it was followed in 1993 by a four-song EP, The Trooper, the title tune a cover of Iron Maiden's classic. This marked the beginning of a shift toward an even more musical, British metal-influenced style, fleshed out on 1995's Amok and the extra EP Erotic love and Death. Jarva left the band at this point, going away guitarist Miika Tenkula and raw vocalist Ville Laihiala as the musical focus of Sentenced. 1997's Down was the outset exertion by this revamped lineup; it was followed in 1998 by Chronicle: A Recollection, a best-of compilation. The group returned in early 2000 with Crimson and once more in 2002 with The Cold White Light.
Wednesday, 4 June 2008
Matrix
Artist: Matrix
Genre(s):
Drum & Bass
Discography:
Sleepwalk
Year: 2000
Tracks: 10
New Identity (NIR12001)
Year: 1996
Tracks: 2
Jamie Quinn is the owner of Metro Records and a frequent recording mate of his chum Matt (aka Optical). The duet debuted on the first two Metro releases, Matrix's "Double Vision" and Optical's "Burnished," and likewise worked together on singles for Positiva and Metalheadz. Solo Matrix tracks throw appeared on Ruff Element, New Identity and Prototype as well. Quinn was the natural pick to mix in the Subway Level 01 assembling in 1999, and he released an album debut (Sleepwalk) the following year.
Footloose - Bacon Returns To Stage With Family Concert
Sunday, 1 June 2008
Jennifer Hudson Tunes Up for Record Release
Effie is finally getting her turn in the spotlight.
Jennifer Hudson, onetime American Idol castoff turned bankable (and Oscar-winning) star in her own right, has finally announced a...
Lily Allen makes light of topless photos
The Smile singer, who was attending a party to celebrate the pending release of the film How To Lose Friends and Alienate People in Cannes, was asked if she minded the topless photographs.
To which she responded, “No, it’s my body.”
She joked: “I heard I was a Page Three girl today.”
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Obituary: Wilfred Middlebrooks
The role of bass players in mainstream jazz is not to attract attention but to support and sustain. This was never better demonstrated than when Wilfred Middlebrooks, who has died aged 74, helped Ella Fitzgerald busk her way through a version of Mack the Knife that gained her a Grammy award. The album in question was Ella in Berlin, a live recording made before an audience of 12,000 people in 1960, and Ella's selection of the song was both spontaneous and seemingly ill-advised, according to Middlebrooks. "My heart sank," he said later. "I knew Ella didn't know the tune and nor did I." Despite several impromptu changes of key and a sense that, "Ella was about as lost as she can get and I was hanging on by a fingernail," her freewheeling performance - described as "hilariously inventive" by one critic - is still talked about today.
Middlebrooks was born in Chattanooga, Tennessee, the son of a bassist who played semi-professionally and a pianist mother. After early piano lessons, he began to dabble with the bass when only 12, encouraged by his grandmother, his obvious promise furthered by lessons with the principal bassist of the Chattanooga Symphony.
Overcome by wanderlust, the 15-year old Middlebrooks left home without a word, his father's bass in tow, to play with a touring carnival show. "First he knew was when I sent a card from San Antonio, Texas. He was going to come after me but I travelled too fast," Middlebrooks told me in 1961, adding that he was about to return the bass to his father after a lapse of a dozen years. The show travelled around the southern states and the young bassist said he learned a lot from his fellow musicians, including the veteran New Orleans trumpeter Punch Miller. He also fathered a couple of children while on the road but made sure, he told me, to stay in touch as they grew up.
When the show stopped off in New York in 1950, Middlebrooks moved over to ex-Basie saxophonist Tab Smith's swing combo, then very popular on the African-American club circuit. Smith toured extensively, the band's recordings revealing Middlebrooks's sturdy line and strong swing feeling. Drafted into the US Army in 1953 and stationed at Camp Stewart, Georgia, he played tuba in the marching band and string bass in the unit dance orchestra. Briefly back with Smith after being demobbed, he opted to settle in California and immediately began to get work with the city's best modern jazz outfits. His main employer was the distinguished reedman Buddy Collette, but Middlebrooks also performed in clubs and on record with instrumentalists like Frank Rosolino, Plas Johnson and Bill Holman.
After Fitzgerald's manager Norman Granz invited him, in 1958, to join her accompanying band, Middlebrooks stayed on the road with the singer for the next five years. Never free for long, they toured endlessly, including four visits to Britain, often in tandem with Jazz at the Philharmonic, Granz's other concert package. There was a slew of Fitzgerald albums, featuring her quartet led by alternating pianists Paul Smith and Lou Levy with Middlebrooks invariably on hand, until he felt he had to call it a day. "Ella simply wore people out," he said. "I was a young cat so I hung in there longer than most, but Ella even wore me out in the end."
Back in Los Angeles, Middlebrooks joined reeds innovator Eric Dolphy's band at Club Oasis, also playing for 13 years with pianist Smith at the Velvet Turtle in Redondo Beach, and recording frequently. He appeared on screen in the 1977 movie New York, New York, cast as - what else? - a bass player. When his jazz work dwindled, Middlebrooks entered the US Postal Service, a haven for many jazz musicians. After retiring in 1991, he resumed freelance playing, often returning to Chattanooga to teach children free at the city's African-American Museum.
Lauded for his "impeccable intonation, sensitivity and sympathetic nature", Middlebrooks is survived by his second wife Ernestine and three children from an earlier marriage.
· Wilfred Roland "Walkin' Willie" Middlebrooks, jazz bassist, born July 17 1933; died March 13 2008
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Madonna joins Rock and Roll Hall of Fame
Madonna was among the artists inducted into the Rock and Roll Hall of Fame in New York last night. To see our gallery from the Hall of Fame ceremony, click here.
Inducting Madonna into the Rock and Roll Hall of Fame, Justin Timberlake said: "She's done it by working harder and being smarter than everybody else. As she made MTV the place to be seen, she racked up the greatest track record in music history - 47 Top 40 hits. She became the biggest name on the planet the old-fashioned way - she earned it."
During her acceptance speech, Madonna said: "It is a great honour to receive this award, and I'm grateful and appreciative for the acknowledgement that this implies."
She also thanked those who had helped her launch her career and quoted from the Talmud.
"I have gone on to do so many things in my life, from writing children's books, to designing clothes, to directing a film. But for me it always does, and it always will, come back to the music, so thank you," she said.
The other stars who joined Madonna on the honour roll were John Mellencamp, Leonard Cohen, the Dave Clark Five and the Ventures.
Blues great Little Walter was posthumously inducted in the sideman category, while production and songwriting legends Kenneth Gamble and Leon Huff received the Ahmet Ertegun Award.
Irish singer-songwriter Damien Rice performed Leonard Cohen's 'Hallelujah" at the ceremony.
Inducting Madonna into the Rock and Roll Hall of Fame, Justin Timberlake said: "She's done it by working harder and being smarter than everybody else. As she made MTV the place to be seen, she racked up the greatest track record in music history - 47 Top 40 hits. She became the biggest name on the planet the old-fashioned way - she earned it."
During her acceptance speech, Madonna said: "It is a great honour to receive this award, and I'm grateful and appreciative for the acknowledgement that this implies."
She also thanked those who had helped her launch her career and quoted from the Talmud.
"I have gone on to do so many things in my life, from writing children's books, to designing clothes, to directing a film. But for me it always does, and it always will, come back to the music, so thank you," she said.
The other stars who joined Madonna on the honour roll were John Mellencamp, Leonard Cohen, the Dave Clark Five and the Ventures.
Blues great Little Walter was posthumously inducted in the sideman category, while production and songwriting legends Kenneth Gamble and Leon Huff received the Ahmet Ertegun Award.
Irish singer-songwriter Damien Rice performed Leonard Cohen's 'Hallelujah" at the ceremony.
Brett Ratner - Ratner Plans Video Game Movies
Filmmaker BRETT RATNER is planning to make a string of video-game inspired movies, after signing a deal with developer Activision.
The Rush Hour director's new company, Brett Ratner Brands, has created commercials for new Activision game Guitar Hero, which aired on U.S. TV during the finale of reality TV hit American Idol on Wednesday (21May08).
And he is hoping to use his relationship with the company to take a slew of computer games to Hollywood.
Ratner tells industry publication Variety, "The games business is much more exciting than the movie business right now. I will be doing movies that come from videogames, (now) I have access to the Activision brain."
Activision is the company behind the Quake, Doom and Call of Duty video game series.
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Ben Affleck - Affleck Garner Sign Up To Help School
Hollywood couple BEN AFFLECK and JENNIFER GARNER are to serve as honorary hosts at a September gala aimed at raising funds for the actress' hometown university in West Virginia.
Officials at the University of Charleston hope people will flock to see the Daredevil stars and help them to raise cash for a new athletics complex, which will house the school's basketball and volleyball programmes.
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McConaughey not interested in marriage
Hollywood star Matthew McConaughey has revealed he has no plans to marry his pregnant girlfriend, Camila Alves.
McConaughey, who is expecting his first child with the Brazilian model, believes he does not need to be a husband to make a good father.
In an interview with The Independent newspaper, the 38-year-old star of 'Failure to Launch' said: "My parents were divorced twice and married three times to each other.
"I believe in the institution of marriage, but I don't feel you have to marry. A kid just needs a mum and a dad."
McConaughey, who famously lives in a trailer on the beach, also revealed he plans for his child to live there too.
He said: "Probably my living in a trailer sounds like I'm just a wanderlust vagabond, but part of it is because I know where my stuff is and how I like it, and there's not enough square footage to have too many places to get lost.
"My child will spend some nights in the trailer. He's going to have culture and travel, but that's one of the great benefits of my business."
McConaughey, who is expecting his first child with the Brazilian model, believes he does not need to be a husband to make a good father.
In an interview with The Independent newspaper, the 38-year-old star of 'Failure to Launch' said: "My parents were divorced twice and married three times to each other.
"I believe in the institution of marriage, but I don't feel you have to marry. A kid just needs a mum and a dad."
McConaughey, who famously lives in a trailer on the beach, also revealed he plans for his child to live there too.
He said: "Probably my living in a trailer sounds like I'm just a wanderlust vagabond, but part of it is because I know where my stuff is and how I like it, and there's not enough square footage to have too many places to get lost.
"My child will spend some nights in the trailer. He's going to have culture and travel, but that's one of the great benefits of my business."
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